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Miami to Panama City

Panama Potpourri

fares from $3,199 per guest
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10-Day Voyage

Sirena

Mar
23
2025
TO
Apr
2
2025
Alternate Dates

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You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action.


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